Lifestyle
7 min read
Navigating Your First Month on a GLP-1: What to Expect
Starting a GLP-1 medication like compounded semaglutide or tirzepatide is an exciting step toward achieving your weight loss goals. However, knowing what to expect during your first month can help you manage your journey more effectively and comfortably.
Here is a guide to navigating your first four weeks on a GLP-1 medication with Fig.
The Titration Process
GLP-1 medications are designed to be introduced to your body gradually. This process is called titration.
During your first month, you will start on the lowest possible dose. This allows your body to adjust to the medication and minimizes the risk of gastrointestinal side effects. It is important to understand that this starting dose is primarily for acclimation, not necessarily for massive weight loss.
Do not be discouraged if you do not see dramatic numbers on the scale in the first few weeks. The goal of the first month is to build tolerance.
Changes in Appetite
Even on the lowest dose, many patients notice a shift in their appetite within the first few days. You may find that you:
Feel full after eating smaller portions.
Have fewer cravings for sugary or high-fat foods.
Think about food less frequently throughout the day (often referred to as a reduction in “food noise”).
This is the medication working to regulate your hunger signals.
Managing Potential Side Effects
Because GLP-1s slow down digestion, gastrointestinal side effects are common, especially when you first start or when you increase your dose. You may experience mild nausea, constipation, or an upset stomach.
To manage these side effects:
Eat smaller, more frequent meals. Avoid large, heavy meals that sit in your stomach.
Stay hydrated. Drink plenty of water throughout the day.
Prioritize protein. Focus on lean proteins to help maintain muscle mass as you lose weight.
Avoid greasy or highly processed foods. These can exacerbate nausea.
Support from Fig
Your Fig care team is here to support you. If you experience uncomfortable side effects or have questions about your progress, you have access to 24/7 unlimited messaging with your dedicated care team through your patient portal.
We will work with you to ensure your titration schedule is appropriate for your individual needs.
Take the free online assessment at Fig today to start your guided weight loss journey.
Medical Disclaimer: Compounded medications are not FDA-approved and have not been evaluated by the FDA for safety, effectiveness, or quality. Fig does not guarantee weight loss results. Individual outcomes vary. Treatment is only prescribed when a licensed provider determines it is clinically appropriate.