What Are GLP-1s? The Science Behind Weight Loss Medications

Quick answer: GLP-1 stands for glucagon-like peptide-1, a hormone your body releases after eating that helps regulate appetite and blood sugar. GLP-1 medications are designed to mimic that activity, supporting reduced appetite and slower stomach emptying. They are prescription treatments that require evaluation by a licensed provider, and results vary by person.

You have likely heard of medications like semaglutide and tirzepatide, but what exactly are they, and how do they work? These medications belong to a class of drugs known as GLP-1 receptor agonists, and they have fundamentally changed how the medical community approaches weight management.

In this article, we explore the science behind GLP-1s and why they are so effective for metabolic health.

Understanding the GLP-1 Hormone

GLP-1 stands for glucagon-like peptide-1. It is a naturally occurring hormone produced in your intestines after you eat a meal. This hormone plays several critical roles in your body:

1. Insulin Regulation: It prompts your pancreas to release insulin, which helps regulate your blood sugar levels.

2. Appetite Signaling: It travels to the brain and binds to receptors that signal you are full, reducing your appetite and cravings.

3. Gastric Emptying: It slows down the rate at which food leaves your stomach, helping you feel satisfied for a longer period.

How GLP-1 Medications Work

GLP-1 receptor agonists, such as semaglutide, are designed to mimic this naturally occurring hormone. However, the medication is engineered to last much longer in your body than your natural GLP-1 hormone, providing sustained appetite control and metabolic regulation.

When you take a GLP-1 medication, it continuously signals to your brain that you are full. This makes it significantly easier to adhere to a reduced-calorie diet, as you are not constantly battling severe hunger cravings.

Dual Agonists: The Next Generation

While semaglutide targets only the GLP-1 receptor, newer medications like tirzepatide are dual agonists. Tirzepatide mimics both GLP-1 and another hormone called GIP (glucose-dependent insulinotropic polypeptide). By targeting two pathways simultaneously, tirzepatide often provides an even more pronounced effect on appetite control and weight loss.

Accessing GLP-1 Medications

At Fig, we provide access to compounded versions of both semaglutide and tirzepatide. These compounded medications are prepared by licensed U.S. pharmacies and contain the same active pharmaceutical ingredients as their brand-name counterparts.

We offer transparent pricing with zero membership fees:

• Compounded Semaglutide: From $145/month (6-month plan)

• Compounded Tirzepatide: From $258/month (6-month plan)

Take the free online assessment at Fig today to see if a GLP-1 medication is the right tool to support your weight loss journey.

Medical Disclaimer: Compounded medications are not FDA-approved and have not been evaluated by the FDA for safety, effectiveness, or quality. Fig does not guarantee weight loss results. Individual outcomes vary. Treatment is only prescribed when a licensed provider determines it is clinically appropriate.

Frequently Asked Questions

What does GLP-1 stand for?

GLP-1 stands for glucagon-like peptide-1, a hormone your body naturally releases after you eat. It helps regulate appetite and blood sugar. GLP-1 medications are designed to mimic this hormone's activity.

How do GLP-1 medications help with weight loss?

They are designed to help by reducing appetite, slowing how quickly your stomach empties, and supporting steadier blood sugar. Many patients find it easier to eat smaller portions and stay consistent. Individual results vary.

Are GLP-1 medications safe for long-term use?

GLP-1 medications have been studied for extended use, and many patients stay on them long term with medical supervision. Regular check-ins with a licensed provider help manage side effects and adjust dosing over time. They are not appropriate for everyone.

How do I know if I qualify for a GLP-1 medication?

Qualification depends on your health history, weight, and goals, and is determined by a licensed provider. With Fig, you can complete a free online assessment in about 5 minutes to see if treatment may be appropriate for you, when prescribed by a licensed provider.

Keep reading

Related: What is Compounded Semaglutide? Safety, Quality, and What You Need to Know

Also helpful: Semaglutide vs. Tirzepatide: Understanding Your Options

Wondering whether GLP-1 treatment could be right for you? Take the free assessment to see if you qualify.