What Are GLP-1s? The Science Behind Weight Loss Medications

You have likely heard of medications like semaglutide and tirzepatide, but what exactly are they, and how do they work? These medications belong to a class of drugs known as GLP-1 receptor agonists, and they have fundamentally changed how the medical community approaches weight management.

In this article, we explore the science behind GLP-1s and why they are so effective for metabolic health.

Understanding the GLP-1 Hormone

GLP-1 stands for glucagon-like peptide-1. It is a naturally occurring hormone produced in your intestines after you eat a meal. This hormone plays several critical roles in your body:

Insulin Regulation: It prompts your pancreas to release insulin, which helps regulate your blood sugar levels.
Appetite Signaling: It travels to the brain and binds to receptors that signal you are full, reducing your appetite and cravings.
Gastric Emptying: It slows down the rate at which food leaves your stomach, helping you feel satisfied for a longer period.

How GLP-1 Medications Work

GLP-1 receptor agonists, such as semaglutide, are designed to mimic this naturally occurring hormone. However, the medication is engineered to last much longer in your body than your natural GLP-1 hormone, providing sustained appetite control and metabolic regulation.

When you take a GLP-1 medication, it continuously signals to your brain that you are full. This makes it significantly easier to adhere to a reduced-calorie diet, as you are not constantly battling severe hunger cravings.

Dual Agonists: The Next Generation

While semaglutide targets only the GLP-1 receptor, newer medications like tirzepatide are dual agonists. Tirzepatide mimics both GLP-1 and another hormone called GIP (glucose-dependent insulinotropic polypeptide). By targeting two pathways simultaneously, tirzepatide often provides an even more pronounced effect on appetite control and weight loss.

Accessing GLP-1 Medications

At Fig, we provide access to compounded versions of both semaglutide and tirzepatide. These compounded medications are prepared by licensed U.S. pharmacies and contain the same active pharmaceutical ingredients as their brand-name counterparts.

We offer transparent pricing with zero membership fees:

Compounded Semaglutide: From $145/month (6-month plan)
Compounded Tirzepatide: From $258/month (6-month plan)

Take the free online assessment at Fig today to see if a GLP-1 medication is the right tool to support your weight loss journey.

Medical Disclaimer: Compounded medications are not FDA-approved and have not been evaluated by the FDA for safety, effectiveness, or quality. Fig does not guarantee weight loss results. Individual outcomes vary. Treatment is only prescribed when a licensed provider determines it is clinically appropriate.